SAPIENS NATURAGROUP

SCIENCE · STRATEGY · DEVELOPMENT

Scientific depth.
Strategic clarity.
Meaningful progress.

We connect science, strategy and execution to create value across pharmaceutical and biotech research and development.

Discover our two divisions ↓
Value creation at the heart of Sapiens Natura Science, research, IP and positioning, development, translation, CRO partnerships, strategy and capital efficiency connect around Sapiens Natura to create scientific, strategic and commercial value. SAPIENS NATURAValuecreationBY DESIGN Science Research IP & positioning Development Translation CRO partnerships Strategy Capital efficiency
SAPIENS NATURAValue
creationBY DESIGN
  • Science
  • Research
  • Strategy
  • Development
  • IP & positioning
  • Translation
  • CRO partnerships
  • Capital efficiency
SCIENTIFIC · STRATEGIC · COMMERCIAL VALUE
Independent thinking. Integrated expertise.

01 / OUR PHILOSOPHY

Good science deserves
a clear path forward.

Drug development brings complex questions. We believe progress starts by connecting the right evidence, expertise and decisions within a coherent development strategy.

At Sapiens Natura, we bring mechanistic insight and translational thinking together with pragmatic execution. Our model combines scientific expertise, lean project execution and capital-efficient development to bridge the gap between promising discoveries and investable pharmaceutical assets.

Scientific rigorIndependent judgmentPurposeful execution

02 / OUR DIVISIONS

Two divisions.
One scientific foundation.

Advising the programs of others.
Building therapeutic innovations of our own.

SNS / 01

Sapiens Natura
Solutions

Scientific strategy & project execution

We work with companies, investors and academic groups to strengthen therapeutic programs from early research and discovery toward clinical development, partnering or investment.

Through R&D strategy, translational planning, IP positioning, CRO coordination and project execution, we help de-risk programs, sharpen their development path and increase their scientific, strategic and commercial value.

  • Scientific and development strategy
  • Translational evidence and program de-risking
  • Decision frameworks and investment narratives
Discuss your program ↗
SNP / 02

Sapiens Natura
Pharma

Project incubation & asset development

We identify scientifically compelling early-stage therapeutic projects and design focused validation programs to de-risk them and build value.

We bring scientific expertise and focused execution together to develop validated assets, with the objective of out-licensing, selling or spinning them out.

  • Early-stage project selection
  • Focused scientific and translational validation
  • Asset development for licensing, sale or spin-out
Explore a collaboration ↗

Sapiens Natura Holding B.V. provides the organizational and operational framework that connects both divisions.

03 / TEAM & EXPERT NETWORK

Connected expertise.
Shared purpose.

Scientific leadership, local AI support and an expert network working together under project-based collaboration agreements. We bring the right expertise into each program, with shared objectives and clear responsibilities.

LEADERSHIPPortrait of Daniel Gironés

Daniel Gironés, PhD

Founder & CEO

With over 20 years in pharmaceutical R&D, Daniel combines scientific leadership with business strategy and an investment perspective. He supports due diligence, program valuation and venture creation, aligning science, IP, capital allocation and partner execution with development, partnering and investment milestones.

LinkedIn
LOCAL AIPortrait of Jane Knightley, Chief AI Assistant

Jane Knightley

Chief AI Assistant

Jane is Sapiens Natura’s local AI assistant, supporting knowledge integration and workflow automation.

Our expert network.

Our specialists work with Sapiens Natura through project-based collaboration agreements. Together, they connect deep scientific expertise with practical development, intellectual property and technology capabilities.

Portrait of Daniel Blanco

Daniel Blanco, PhD

Organic chemistry & structural elucidation

Expertise in complex organic synthesis for pharmaceutical applications and NMR spectroscopy, connecting molecule design, synthesis and structural characterization.

Portrait of Byron Martina

Byron Martina, PhD

Virology & immunology

Experience in infectious diseases, vaccine research and antiviral therapeutics, combining cell biology and robust assay development with translational strategies.

Portrait of Jianmin Duan

Jianmin Duan, PhD

ADME, PK/PD & pharmacology

Over 20 years of experience in drug absorption, distribution, metabolism and pharmacology. Expertise in experimental design, bioavailability optimization and PK/PD modeling.

Portrait of Valeria de Matteis

Valeria de Matteis, PhD

Intellectual property strategy

European Patent Attorney with a research background in organic chemistry and experience in pharmaceutical companies and patent law firms. Expertise in patent drafting, portfolio management and freedom-to-operate analysis.

Portrait of Ellert van Koperen

Ellert van Koperen

Pharma IT & data systems

Connects scientific needs with reliable digital infrastructure, spanning data pipelines, computational chemistry tools and collaboration systems, with specialist expertise in PostgreSQL and database performance.

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ADDITIONAL SPECIALIST EXPERTISE

Capabilities that connect
the development path.

Computational chemistry

Structure- and ligand-based drug design, molecular modeling, chemoinformatics, SAR and screening-data analysis to support lead optimization.

Regulatory affairs

Specialist input on Drug Master Files and pharmaceutical dossiers, bringing regulatory considerations into early development decisions.

PK modeling

Pharmacokinetic modeling to characterize drug exposure, inform dose selection and connect experimental data with development decisions.

01

Scientific expertise

Biology, medicinal chemistry, pharmacology and PK/PD, connected by translational thinking.

02

Development expertise

Intellectual property, chemistry, manufacturing and controls (CMC), and regulatory expertise aligned with each program’s development path.

03

Integrated execution

Project teams that connect specialist expertise and CRO execution, with strong scientific oversight and clear priorities.

04 / CONTACT

Let’s give your science
a clear direction.

Discuss a development challenge, a therapeutic opportunity or a potential collaboration.

Portrait of Jane Knightley, Chief AI Assistant
Your point of contact

Jane Knightley

Chief AI Assistant

Jane is Sapiens Natura’s local AI assistant, supporting knowledge integration and workflow automation.

Sapiens Natura Group
Geert Grooteplein Zuid 41
6525 GA Nijmegen
The Netherlands

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